The Hotel del Luna (formally referred to as the "Guest House of the Moon"), located in Seoul, is not like any other hotel: its clients are all ghosts and is not visible in its true form during the day. During the Goguryeo era, a rebel named Jang Man-wol (Lee Ji-eun) drank a liquor that unknowingly turned her into the guest house's owner while she was traveling to find it. She has been stuck running the hotel for the past millennium before meeting Ku Chan-Seong (Yeo Jin-goo), the new manager.
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2019年,首尔市内变化最大的市中心正中间,位置于黄金宝地 — 明洞的古老破旧建筑物,乍一看就像准备重建的空建筑物,但仔细地看的话,其实是经营中的酒店。
如果早上的话,在那前面有数百万的流动人口经过,却几乎没有客人进入那酒店里面。而在开始入夜、路上变得更冷清、市中心也入睡之时,招牌便著灯光,酒店楼层亦会升高的....德鲁纳酒店。
灵宾专用的德鲁纳酒店里,超精英酒店管理人具灿星担任著总经理,和乖戾、脾气暴躁的社长张满月一起,为特别的灵魂客人们提供特级服务时发生的故事。